A SINGLE-DOMAIN ANTIBODY TARGETING COMPLEMENT COMPONENT C5 ACTS AS A SELECTIVE INHIBITOR OF THE TERMINAL PATHWAY OF THE COMPLEMENT SYSTEM AND THUS FUNCTIONALLY MIMICKS THE C-TERMINAL DOMAIN OF THE STAPHYLOCOCCUS AUREUS SSL7 PROTEIN

The complement system is an efficient anti-microbial effector mechanism.On the other hand abnormal complement activation is involved in the pathogenesis of multiple inflammatory and hemolytic diseases.As general inhibition of the complement system may jeopardize patient health due to increased susceptibility to infections, the development of pathwa

Abstract Background Recognising the influence of context and the context-sensitive nature of quality improvement (QI) interventions is crucial to implementing effective improvements and successfully replicating them in new settings, yet context is still poorly understood.To address this challenge, it is necessary to capture generalisable knowledge,

Burn injuries are complex and challenging, requiring a multidisciplinary approach.We have done Thermistors more than 15 cases of severely distorted airways in patients with burns (photos attached); although the basic case management remains the same, there are a plethora of other concerns that make these patients unique.The most unique and severe 1

The countries of the Gulf Cooperation Council (GCC) have both large fossil fuel resources and vast renewable energy potentials.Here, we investigate in a literature meta-analysis and a survey, whether there is a need for renewables in the GCC, what barriers and risks presently deter investments, and what possible policy-solutions could be.We find th

Membrane fouling has been a major issue in the development of more efficient water treatment processes.Specifically in surface waters filtration, organic matter, such as humic-like substances, can cause irreversible fouling.Therefore, this study evaluates the activity of a photocatalytic layer composed of Ce-doped zirconia nanoparticles in improvin